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PTD - 241

Test Directory - Growth Hormone

Synonyms

hGH

Clinical Indications

Random Growth Hormone (GH) measurements are of limited value. Dynamic tests are required for proper diagnosis. For investigation of acromegaly a IGF1 level or growth hormone suppression test is of greater value.

Request Form

Combined Pathology Blood form (Yellow/Black)

Availability

Referred test: Analysed by Clinical Biochemistry, Southend Hosptial if specific criteria met.

Specific Criteria

Requested by Consultant Endorcrinologists or agreed with Consultant Biochemist. Part of growth hormone suppression test or GH stimulation tests (insulin stress test).

Patient Preparation

It is advisable to avoid stress. 

Turnaround Time

Two weeks.

Specimen

Serum

Volume

1 ml

Container

   

Yellow top (SST) or Red top (plain) tube

 

For paediatrics a orange top (lithium-heparin) or brown top (serum) tube should be collected.

Causes for Rejection

Not meeting specific criteria for analysis. Unlabelled sample.

Reference Range

Random GH levels are of limited value due to pulsatile release and a low random GH is not diagnostic of deficiency. A level below 0.4 ug/L with a normal IGF-1 excludes acromegaly.

Reference: Katznelson L, Atkinson JLD, Cook DM, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly - 2011 update. Endocr Pract. 2011;17(Suppl 4):1-44

Lab. Handling

Processing: Aliquot and freeze at -20C in separating freezer (CB40), active frozen rack 110. Stable at 4C off the red cells for up to 7 hours.
Referral:
GH and send frozen in the transport box to the referral laboratory or NOGH and save in separating freezer (CB40) at -20C, saved frozen rack.


Version 1.1 / September 2014                                                                                                 Approved by: Consultant Biochemist