This enzyme is a sensitive
marker of liver insult; it is raised in cases of excessive
alcohol consumption, when other liver markers may be normal.
gamma-GT is a poor
marker of alcohol intake – if raised as a result of alcohol
damage it may never return to normal, even if total
(e.g. phenytoin) act as an enzyme inducer and gamma-GT
levels may be elevated in the absence of liver pathology.
most useful in distinguishing between bone and liver causes
of a raised alkaline