return to G index

return to index page

PTD - 238

Test Directory - Gamma-GT

Synonyms

GGT

Clinical Indications

This enzyme is a sensitive marker of liver insult; it is raised in cases of excessive alcohol consumption, when other liver markers may be normal. However gamma-GT is a poor marker of alcohol intake if raised as a result of alcohol damage it may never return to normal, even if total abstinence.

Some drugs (e.g. phenytoin) act as an enzyme inducer and gamma-GT levels may be elevated in the absence of liver pathology.

Gamma-GT is most useful in distinguishing between bone and liver causes of a raised alkaline phosphatase level.

Request Form

Combined Pathology Blood form (Yellow/Black)

Availability

On request.

Specific Criteria

None

Patient preparation

None

Turnaround Time

Same day

Specimen

Serum

Volume

1 ml

Container


Yellow top (SST) tube or


Paediatric orange top (lithium-heparin)

Causes for Rejection

Unlabelled sample.

Reference Range

Males: 10 - 71 IU/L.
Females:  6 - 42  IU/L

Reference: Roche method insert

Lab Handling

Processing: Analysed from primary tube and stored at 4C in the cold room (CB23)


Version 1.1 /  October 2014                                                                                                    Approved by: Consultant Biochemist