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PTD-261

Test Directory - Myelin-associated Glycoprotein Antibodies

Synonyms

MAG antibodies

Clinical Indications

Investigation of patients with sensory-motor neuropathies.

Request Form

Combined Pathology Blood form (Yellow/Black)

Availability

Referral test: Analysed by Immunology, National Hospital.

Specific Criteria

Requested by Consultant Neurologist and must have confirmed IgM paraprotein. For a known positive patient, it is not usual to monitor levels as the antibodies will not disappear even when the patient is treated.

Patient Preparation

 

None required

Turnaround Time

1 month

Specimen

Serum

Volume

1 ml

Container

Yellow top (SST) tube or

Paediatric orange top (lithium-heparin)

Causes for Rejection

Not meeting specific criteria for analysis. No re-test within one year. Once positive, it is not necessary to monitor levels as the antibodies will not disappear when the patient is on treatment.

Reference range

 

Negative

Interpretation

Samples are screened by ELISA for IgM antibodies against myelin-associated glycoprotein.  Positive screens are titrated to measure the level. 

Lab handling

 

Processing: Aliquot (MPA) and store at 4C in separating fridge (CB39), referral rack.
Referral
:  MAGAB and send or BPRO and track at -20C in separating freezer (CB40).


 Version 1.0 / July 2014                                                                                                           Approved by: Consultant Biochemist