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Test Directory -  Oestradiol

Synonyms

Estradiol, E2

Clinical Indications

Investigation of amenorrhoea. Investigation of gynaecomastia in men. Monitoring of patients with HRT (oestradiol) implants. There is little value in measuring oestradiol for monitoring of oral HRT or patches other than testing for non-compliance or non-absorption.

Oestradiol levels are of no value in investigation of menopause since levels may remain normal for several months following menopause (please refer to protocol on investigation of menopause).

Request Form 

Combined Pathology Blood form (Yellow/Black or Blue for GP's).

Availability

Analysed on request.

Specific Criteria

None.

Patient Preparation

None.

Turnaround Time

Same day

Specimen

Serum

Volume

1.0 mL

Container

Yellow Top  (SST) tube

Collection

Samples should be transported to laboratory immediately.

Reference ranges

Adult females   Oestradiol (pmol/L)
Follicular phase   100  - 610
Mid-cycle   570 - 1,620
Luteal phase   200 - 730

HRT Implants: in order to avoid tachyphylaxis measure oestradiol before next implant and adjust dose of implant as follows:

Implant dose   Oestradiol (pmol/L)
100 mg   Less than 250
50 mg   250 - 749
25 mg   750 - 1,000
Nil   >1,000

Causes for Rejection

Unlabelled sample.

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Last edited 16/04/14