PTD - 40

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Test Directory - Platelet Antibodies

Synonyms

Clinical Indications

To determine the presence of platelet antibodies that are associated with disease and drug therapies.

Request Form

Combined Pathology Blood form (Yellow/Black or Blue for GP's)Blood Transfusion form (Pink) following discussion with or requested by Consultant Haematologists.

Availability

Analysed by referral laboratory if specific criteria met.

Specific Criteria

Requested by Consultant or agreed with Consultant Haematologists or as requested by the NBS.

Turnaround Time

Usually within two months

Specimen

Dependant on clinical indication. Requestor will be directed on a case by case basis by the laboratory.

Volume

Dependant on clinical data

Container

Dependant on clinical data

Collection

Samples should be transported to laboratory immediately.

Lab. Handling

Samples should be sent to Reference Laboratory as soon as possible must be received at reference centre within 72 hours

Causes for Rejection

Unlabelled / unsigned sample. Incorrect or inadequate patient identifiers provided. Insufficient sample volume. Poor sample quality due to deterioration, haemolysis or clot (in EDTA)

Limitations

  Delay in delivery to Reference centre (Bristol) - must be within 72 hours

Interpretation

Low platelet counts in newborn infants are occasionally as a result of parental platelet antibodies. Investigations should therefore include samples of both parents and the child after ruling out other clotting abnormalities. Thrombocytopenia in adults may be due to many causes, including drug induced reactions to antibiotics, quinine and heparin with the patient producing antibodies. Alternative therapies may provide a solution.

        

 


Version 1.0 / January 2013